| Delayed defibrillation testing in patients implanted with biventricular ICD (CRT-D): a reliable and safe approach. | |
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MedLine Citation:
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PMID: 16403056 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Defibrillation testing (DT) at the end of the implantation of cardiac resynchronization pacemaker with a defibrillator (CRT-D) exposes heart failure (HF) patients to increased procedural risks. However, until now, delayed DT has not been assessed as a possible option in HF patients implanted with CRT-D. OBJECTIVE: Aim of the present study is to assess safety and feasibility of delayed DT in HF patients treated with CRT-D. MATERIAL AND METHODS: Two hundred and eleven consecutive patients (mean age: 65 years, mean NYHA class 3.0, mean EF: 29.3%) underwent CRT-D implantation from October 1999 to December 2004. In the first 17 patients, DT was performed at the end of CRT-D implantation. In the other 194 consecutive patients, DT was performed at 2 months after CRT-D implantation. Outcome of DT, as well as "acute" LV lead dislodgment rate were evaluated in the latter group of 194 patients undergoing a delayed DT. Also, ICD function was assessed through device telemetry analysis at 2 months. RESULTS: At delayed DT, first shock was effective in 187 of 194 patients (96%), ineffective VF interruption at maximum energy occurred only in one patient (0.5%), and acute LV lead dislodgment was 1%. No ICD therapy failure occurred in the 2-month untested period. CONCLUSION: DT performed 2 months after CRT-D implantation is safe and feasible; this is possibly related to the improvement of clinical conditions and hemodynamic status as well as greater lead stability 2 months after CRT-D. |
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Authors:
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Maurizio Gasparini; Paola Galimberti; François Regoli; Carlo Ceriotti; Marika Bonadies |
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Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Journal of cardiovascular electrophysiology Volume: 16 ISSN: 1045-3873 ISO Abbreviation: J. Cardiovasc. Electrophysiol. Publication Date: 2005 Dec |
Date Detail:
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Created Date: 2006-01-11 Completed Date: 2006-03-07 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9010756 Medline TA: J Cardiovasc Electrophysiol Country: United States |
Other Details:
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Languages: eng Pagination: 1279-83 Citation Subset: IM |
Affiliation:
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Electrophysiology and Pacing Unit, Istituto Clinico Humanitas, Via Manzoni, Rozzano Milano, Italy. maurizio.gasparini@humanitas.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Aged Cardiac Pacing, Artificial / adverse effects* Defibrillators, Implantable / adverse effects* Electric Countershock / instrumentation* Feasibility Studies Female Heart Failure / therapy* Heart Ventricles / physiopathology* Humans Male Middle Aged Safety Time Factors |
| Comments/Corrections | |
Comment In:
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J Cardiovasc Electrophysiol. 2005 Dec;16(12):1284-5
[PMID:
16403057
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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