Document Detail


Delayed arousal.
MedLine Citation:
PMID:  19825485     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Elderly patients have medical and psychological problems affecting all major organ systems. These problems may alter the pharmacokinetics and/or pharmacodynamics of medications, or expose previous neurologic deficits simply as a result of sedation. Delayed arousal, therefore, may arise from structural problems that are pre-existent or new, or metabolic or functional disorders such as convulsive or nonconvulsive seizures. Determining the cause of delayed arousal may require clinical, chemical, and structural tests. Structural problems that impair consciousness arise from a small number of focal lesions to specific areas of the central nervous system, or from pathology affecting the cerebrum. In general, focal or multifocal lesions can be identified by computerized tomography, or diffusion-weighted imaging. An algorithm is presented that outlines a workup for an elderly patient with delayed arousal.
Authors:
Zirka H Anastasian; Eugene Ornstein; Eric J Heyer
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Anesthesiology clinics     Volume:  27     ISSN:  1932-2275     ISO Abbreviation:  Anesthesiol Clin     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-10-14     Completed Date:  2009-12-30     Revised Date:  2011-07-25    
Medline Journal Info:
Nlm Unique ID:  101273663     Medline TA:  Anesthesiol Clin     Country:  United States    
Other Details:
Languages:  eng     Pagination:  429-50, table of contents     Citation Subset:  IM    
Affiliation:
Division of Neurosurgical Anesthesiology, Department of Anesthesiology, Columbia University, New York, NY 10032, USA. zh2114@columbia.edu
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MeSH Terms
Descriptor/Qualifier:
Aged
Anesthesia Recovery Period*
Arousal / drug effects,  physiology*
Brain / physiology
Consciousness / drug effects,  physiology
Female
Humans
Neural Pathways / physiology
Neuroma, Acoustic / complications,  surgery
Postoperative Complications / therapy*
Seizures / complications
Grant Support
ID/Acronym/Agency:
R01 AG017604-05A2/AG/NIA NIH HHS; R01-AG16404/AG/NIA NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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