Document Detail


Delayed appearance of a circulating myocardial depressant factor in burn patients.
MedLine Citation:
PMID:  7458026     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fourteen burn patients and four normal controls were studied for the plasma activity of a myocardial depressant factor (MDF). The mean age of the burn patients was 40.4 years and the burn area was 61.9% of body surface. MDF activities were 28 +/- 3 units in the burn patients on day 1 and 56 +/- 4 units on days 4 and 5. This compares with 23 +/- 3 units for the control patients. Despite maintenance of high cardiac output by fluid therapy, only three of the 14 patients (21%) survived. Our data show the presence in burn patients of MDF, which may contribute to high mortality rates in these patients.
Authors:
D De Santis; P Phillips; M A Spath; A M Lefer
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Annals of emergency medicine     Volume:  10     ISSN:  0196-0644     ISO Abbreviation:  Ann Emerg Med     Publication Date:  1981 Jan 
Date Detail:
Created Date:  1981-03-24     Completed Date:  1981-03-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8002646     Medline TA:  Ann Emerg Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  22-4     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Burns / blood*,  complications,  mortality
Female
Fluid Therapy
Humans
Male
Middle Aged
Myocardial Depressant Factor / blood*
Peptides / blood*
Shock / blood*,  etiology,  mortality
Time Factors
Chemical
Reg. No./Substance:
0/Myocardial Depressant Factor; 0/Peptides

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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