Document Detail

Delay in presentation and diagnosis of adult primary intracranial neoplasms in a tropical teaching hospital: a pilot study.
MedLine Citation:
PMID:  19595802     Owner:  NLM     Status:  MEDLINE    
Sixty-three adult patients with intracranial neoplasms were studied prospectively over a 2 year period. The various factors related to pre-presentation symptoms interval (PSI) and pre-diagnostic interval (PI) were noted. The mean age at presentation for all patients was 46.8 years (range 18-72 years, median 46 years). Meningiomas (30%), Pituitary tumours (18%), High-grade gliomas (14%) and craniopharyngiomas (8%) were the most common brain tumours. The median PSI of all patients was 2 year (range 2 months-5 years) with a PI of 4 weeks (range 0-8 months). The PSI and PI were longer for women with a statistical significance between the PSI and gender (p=0.016). The tumour grade was significantly correlated with PSI (p=0.000) and PI (p=0.043). Late presentation and diagnosis were due to cultural and religious beliefs compounded by self medication and financial constraint. There is the need for widespread mass enlightenment, improvement in accessibility and affordability of neuroimaging facilities coupled with subsidization of treatment.
O E Idowu; R A Apemiye
Publication Detail:
Type:  Journal Article     Date:  2009-07-10
Journal Detail:
Title:  International journal of surgery (London, England)     Volume:  7     ISSN:  1743-9159     ISO Abbreviation:  -     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-08-25     Completed Date:  2009-12-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101228232     Medline TA:  Int J Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  396-8     Citation Subset:  IM    
Division of Neurological Surgery, Department of Surgery, Lagos State University College of Medicine (LASUCOM), Lagos State University Teaching Hospital (LASUTH), Ikeja, Lagos, Nigeria.
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MeSH Terms
Biopsy, Needle
Brain Neoplasms / diagnosis*,  mortality*,  pathology,  surgery
Cause of Death*
Developing Countries
Early Detection of Cancer
Health Services Accessibility*
Hospitals, Teaching
Middle Aged
Needs Assessment
Neoplasm Invasiveness / pathology*
Neoplasm Staging
Pilot Projects
Prospective Studies
Risk Assessment
Survival Analysis
Time Factors
Tropical Climate
Young Adult
Comment In:
Int J Surg. 2009 Oct;7(5):485   [PMID:  19635600 ]

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