Document Detail


Delay in thrombolysis of massive and submassive pulmonary embolism.
MedLine Citation:
PMID:  20547548     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Objective: To report the time of delay in thrombolysis of massive and submassive pulmonary embolism (PE). Methods: We enrolled 83 consecutive patients with massive and submassive PE from 8 hospitals between June 2006 and March 2009. We recorded the delay between symptom onset and thrombolysis. The clinical findings related to early thrombolysis (delay ≤2 days) were analyzed. Results: Median of the delay in thrombolysis was 8 days with 82% over 2 days, 53% over 7 days, and 6% over 25 days. Compared to the late thrombolysis (delay >2 days), patients with early thrombolysis more frequently had murmurs at the tricuspid area (26.7% vs 6.1%, P = .053), less frequently had cough (20% vs 59.7%, P = .005) and increased P2 (pulmonic component of second heart sound; 33.3% vs 61.2%, P = .049), and more patients were thrombolysed in off-hours (86.7% vs 57.4%, P = .034). Conclusion: The time of delay in thrombolysis is too long and the symptoms and signs between early and late thrombolysis groups may differ.
Authors:
Yang Wang; Yuanhua Yang; Chen Wang; Zhuang Ma; Chen Qiu; Hua Wu; Jin Zhang; Xiaoyun Hu; Zhenguo Zhai; Wanmu Xie; Changting Liu;
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Publication Detail:
Type:  Journal Article     Date:  2010-06-13
Journal Detail:
Title:  Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis     Volume:  17     ISSN:  1938-2723     ISO Abbreviation:  Clin. Appl. Thromb. Hemost.     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-09-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9508125     Medline TA:  Clin Appl Thromb Hemost     Country:  United States    
Other Details:
Languages:  eng     Pagination:  381-6     Citation Subset:  IM    
Affiliation:
Nanlou Respiratory Diseases Department, Chinese PLA General Hospital, Chinese PLA Postgraduate Medical School, Beijing, People's Republic of China, Beijing Institute of Respiratory Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People's Republic of China.
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