| Delay Correction for the Assessment of Blood-Brain Barrier Permeability Using First-Pass Dynamic Perfusion CT. | |
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MedLine Citation:
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PMID: 20538824 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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SUMMARY: Hemorrhagic transformation is a serious potential complication of ischemic stroke with damage to the BBB as one of the contributing mechanisms. BBB permeability measurements extracted from PCT by using the Patlak model can provide a valuable assessment of the extent of BBB damage. Unfortunately, Patlak assumptions require extended PCT acquisition, increasing the risk of motion artifacts. A necessary correction is presented for obtaining accurate BBB permeability measurements from first-pass PCT. |
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Authors:
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T Schneider; J Hom; J Bredno; J W Dankbaar; S-C Cheng; M Wintermark |
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Publication Detail:
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Type: Journal Article Date: 2010-06-10 |
Journal Detail:
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Title: AJNR. American journal of neuroradiology Volume: 32 ISSN: 1936-959X ISO Abbreviation: AJNR Am J Neuroradiol Publication Date: 2011 Aug |
Date Detail:
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Created Date: 2011-08-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8003708 Medline TA: AJNR Am J Neuroradiol Country: United States |
Other Details:
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Languages: eng Pagination: E134-8 Citation Subset: IM |
Affiliation:
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Department of Radiology, Neuroradiology Section. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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