| Degradation of bacterial lipopolysaccharide by the slime mould Physarum polycephalum. | |
| | |
MedLine Citation:
|
PMID: 373869 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
A strain of the acellular slime mould Physarum polycephalum degraded lipopolysaccharides (LPS) from a variety of bacteria. The anticomplementary (AC) activity of LPS was greatly reduced, as was the content of lauric, myristic, and palmitic acids, and the ability to sensitize erythrocytes to agglutination by antibody. These results indicate that Physarum has enzymes which reduce the lipid A moiety of LPS. In contrast, 2-keto-3-deoxy-D-manno-actanoic acid (KDO), immunodominant sugars, and beta-hydroxymyristic acid were scarcely affected. Both supernates and plasmodial extracts of Physarum had LPS-degradative activity and were able to attack both purified LPS and LPS in killed bacteria. |
| | |
Authors:
|
J N Saddler; J G Coote; A C Wardlaw |
Related Documents
:
|
7295649 - Carbon-13 nuclear magnetic resonance spectroscopic study of teichuronic acid from micro... 18316129 - Methodology to label mixed carbohydrate components by apts. 11791709 - Structural characterization and immunomodulating activity of a complex glucan from spor... 404289 - Metabolic role of free mycolic acids in mycobacterium tuberculosis. 236829 - The structure of klebsiella serotype ii capsular polysaccharide. 196639 - Structural studies on the sialic acid polysaccharide antigen of escherichia coli strain... 14197889 - Amino acid accumulation in ethionine-resistant saccharomyces cerevisiae. 1980429 - Reexamination of dopamine as the prolactin-release inhibiting factor (pif): supplementa... 3747739 - Effect of nutritional status on the fatty acid composition of rat liver and cultured he... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Canadian journal of microbiology Volume: 25 ISSN: 0008-4166 ISO Abbreviation: Can. J. Microbiol. Publication Date: 1979 Feb |
Date Detail:
|
Created Date: 1979-07-16 Completed Date: 1979-07-16 Revised Date: 2008-11-21 |
Medline Journal Info:
|
Nlm Unique ID: 0372707 Medline TA: Can J Microbiol Country: CANADA |
Other Details:
|
Languages: eng Pagination: 124-9 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Biodegradation, Environmental Escherichia coli Hemagglutination Inhibition Tests Hot Temperature Lipopolysaccharides / analysis, immunology, metabolism* Physarum / metabolism* Salmonella |
| Chemical | |
Reg. No./Substance:
|
0/Lipopolysaccharides |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Bile acids of a 3200-year-old Egyptian mummy.
Next Document: Effect of cardiopulmonary bypass and hypothermia on pancreatic endocrine function and peripheral uti...