| Degenerative mitral valve regurgitation: understanding basic concepts and new developments. | |
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MedLine Citation:
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PMID: 21474894 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Chronic degenerative mitral regurgitation is the most common valvular disease in the United States. The objective of this review article is to impart a balanced understanding of the basic concepts and new developments in assessment and management of patients with severe degenerative mitral regurgitation. Etiologic, epidemiologic, pathologic, and physiopathologic concepts are discussed, as well as the importance of surgical mitral valve repair as the current gold standard treatment. Research efforts in "decoding" the natural history and prognosis of patients with severe degenerative mitral regurgitation have produced important insights into the surgical timing of patients with asymptomatic mitral regurgitation, and the concept of early restorative surgery has emerged. |
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Authors:
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Hector I Michelena; Yan Topilsky; Rakesh Suri; Maurice Enriquez-Sarano |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Postgraduate medicine Volume: 123 ISSN: 1941-9260 ISO Abbreviation: Postgrad Med Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-04-08 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401147 Medline TA: Postgrad Med Country: United States |
Other Details:
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Languages: eng Pagination: 56-69 Citation Subset: AIM; IM |
Affiliation:
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Mayo Clinic, Rochester, MN. michelena.hector@mayo.edu. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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