Document Detail

Degeneration and ossification of the yellow ligament in unstable spine.
MedLine Citation:
PMID:  1724936     Owner:  NLM     Status:  MEDLINE    
Lumbar yellow ligaments were obtained from 20 cases of lumbar spinal canal stenosis and 20 cases of degenerative olisthesis with slippage of more than 3 mm. The ligaments were stained with safranin-O, von Kossa, and immunohistochemical staining methods (S-100 protein). In the unstable group the safranin-O staining was more intense, microscopic ossification and chondroblasts were noted more frequently, and S-100 protein was more abundant. These findings show that instability of the lumbar spine accelerates degeneration and chondrometaplasia of the yellow ligament, which may lead to the enchondral ossification of the ligament.
T Nakamura; N Hashimoto; Y Maeda; T Ikeda; H Nakagawa; K Takagi
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of spinal disorders     Volume:  3     ISSN:  0895-0385     ISO Abbreviation:  J Spinal Disord     Publication Date:  1990 Dec 
Date Detail:
Created Date:  1992-04-30     Completed Date:  1992-04-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8904842     Medline TA:  J Spinal Disord     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  288-92     Citation Subset:  IM    
Department of Orthopaedic Surgery, Kumamoto University, Medical School, Japan.
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MeSH Terms
Calcinosis / etiology*
Cartilage / pathology
Joint Instability / complications*,  pathology
Ligaments / chemistry,  pathology*
Lumbar Vertebrae*
Middle Aged
Proteoglycans / analysis
Spinal Stenosis / complications,  pathology
Spondylolisthesis / complications*,  pathology
Staining and Labeling
Reg. No./Substance:

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