| Degeneration of the Arnold's prefrontopontocerebellar tract in a case of locked-in syndrome over a 23-year period. | |
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MedLine Citation:
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PMID: 21093914 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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A 52-year-old woman has been under observation for a complete locked-in syndrome of vascular origin, since 1984. Her cognitive functions today are still normal. When first diagnosed, a CT-scan was made and 23 years later performed, a cerebral MRI was performed. A focal, bilateral and symmetric atrophy of the dorsomedial prefrontal gyri was clearly shown, contrasting with the non-atrophy of the precentral gyri (motor area), others prefrontal areas, frontopolar gyri and temporal cortices. Degeneration of the corticopontine projection, the first step in the corticopontocerebellar circuit, could explain this selective atrophy. This unique observation leads to the precise in vivo anatomical location of the Arnold tract. |
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Authors:
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François Cotton; Sophie Ciancia; Laurence Tell; Laurence Lachaise; Marc Braun; Gilles Rode |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2010-11-18 |
Journal Detail:
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Title: Journal of neuroradiology. Journal de neuroradiologie Volume: - ISSN: 0150-9861 ISO Abbreviation: J Neuroradiol Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-11-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7705086 Medline TA: J Neuroradiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2010 Elsevier Masson SAS. All rights reserved. |
Affiliation:
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Laboratoire d'anatomie de Rockefeller, université de Lyon 1, Lyon, France; Service de radiologie, centre hospitalier Lyon Sud, hospices civils de Lyon, 69495 Pierre-Bénite cedex, France; Creatis-LRMN, CNRS UMR 5220, Inserm U630, université de Lyon 1, 69621 Villeurbanne cedex, France. |
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