Document Detail

Defragmentation of low grade day 3 embryos resulted in sustained reduction in fragmentation, but did not improve compaction or blastulation rates.
MedLine Citation:
PMID:  20403590     Owner:  NLM     Status:  MEDLINE    
In a prospective randomized fashion, this study evaluated embryo development in vitro after defragmentation versus assisted hatching alone of low grade day 3 embryos. Although a sustained decrease in day 5 fragmentation was observed in the defragmented group versus the assisted hatching only group, no difference in compaction rates or blastula formation rates were appreciated.
Martin Keltz; Rani Fritz; Eric Gonzales; Serhan Ozensoy; Josh Skorupski; Daniel Stein
Publication Detail:
Type:  Journal Article     Date:  2010-04-18
Journal Detail:
Title:  Fertility and sterility     Volume:  94     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-10-27     Completed Date:  2010-12-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2406-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, St. Luke's Roosevelt Hospital Center, Columbia University College Of Physicians and Surgeons, New York, New York 10019, USA.
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MeSH Terms
Blastocyst / cytology*,  metabolism
Blastula / cytology*,  metabolism
Case-Control Studies
Cell Count
Cleavage Stage, Ovum / cytology*
DNA Packaging / genetics,  physiology*
Embryo Culture Techniques / methods
Embryo Disposition
Embryonic Development / physiology
Quality Control
Random Allocation
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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