Document Detail


Defragmentation of low grade day 3 embryos resulted in sustained reduction in fragmentation, but did not improve compaction or blastulation rates.
MedLine Citation:
PMID:  20403590     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In a prospective randomized fashion, this study evaluated embryo development in vitro after defragmentation versus assisted hatching alone of low grade day 3 embryos. Although a sustained decrease in day 5 fragmentation was observed in the defragmented group versus the assisted hatching only group, no difference in compaction rates or blastula formation rates were appreciated.
Authors:
Martin Keltz; Rani Fritz; Eric Gonzales; Serhan Ozensoy; Josh Skorupski; Daniel Stein
Publication Detail:
Type:  Journal Article     Date:  2010-04-18
Journal Detail:
Title:  Fertility and sterility     Volume:  94     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-10-27     Completed Date:  2010-12-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2406-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Affiliation:
Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, St. Luke's Roosevelt Hospital Center, Columbia University College Of Physicians and Surgeons, New York, New York 10019, USA. mdkeltz@aol.com
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MeSH Terms
Descriptor/Qualifier:
Blastocyst / cytology*,  metabolism
Blastula / cytology*,  metabolism
Case-Control Studies
Cell Count
Cleavage Stage, Ovum / cytology*
DNA Packaging / genetics,  physiology*
Embryo Culture Techniques / methods
Embryo Disposition
Embryonic Development / physiology
Female
Humans
Male
Pregnancy
Quality Control
Random Allocation
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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