Document Detail

Deformation characteristics of a bioabsorbable intravascular stent.
MedLine Citation:
PMID:  1473918     Owner:  NLM     Status:  MEDLINE    
RATIONALE AND OBJECTIVES: Biodegradable polymeric stents offer an alternative to metallic stents, which have a significant compliance mismatch with blood vessels and have the potential for long-term complications. In the current study, the deformation characteristics of polymeric stents have been investigated. METHODS: Stents were subjected to radial compressive pressure by inserting them in a wrap-around collar, one end of which was loaded in tension using dead-weights. The resulting decrease in stent diameter was measured under an optical microscope. Deformation curves for the stents were plotted, and an effective stiffness, E', was determined for each. RESULTS: The deformation curves exhibited two different regions: an initial linear region, followed by a steep nonlinear region. The transition from the linear region occurred at a fractional decrease in stent diameter of approximately 0.5. CONCLUSION: E' decreases with increasing stent diameter and filament draw-ratio. The relationship between E' and the initial stent diameter is not linear. The deformation curves can be used for choosing the appropriate stents for specific applications.
C M Agrawal; H G Clark
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Publication Detail:
Type:  In Vitro; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Investigative radiology     Volume:  27     ISSN:  0020-9996     ISO Abbreviation:  Invest Radiol     Publication Date:  1992 Dec 
Date Detail:
Created Date:  1993-01-29     Completed Date:  1993-01-29     Revised Date:  2010-03-24    
Medline Journal Info:
Nlm Unique ID:  0045377     Medline TA:  Invest Radiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1020-4     Citation Subset:  IM    
Orthopaedic Research Division, University of Texas Health Science Center, San Antonio 78284-7774.
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MeSH Terms
Biodegradation, Environmental
Blood Vessels*
Lactic Acid*
Reg. No./Substance:
0/Lactates; 0/Polymers; 26100-51-6/poly(lactic acid); 50-21-5/Lactic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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