Document Detail


Deformability and enzymes activities of red blood cells in hemodialysed and peritoneal dialysed patients with chronic renal disease.
MedLine Citation:
PMID:  12897415     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
These studies were focused on the influence of two treatment methods of patients with chronic renal disease on RBC deformability. In peritoneal dialysed-patients (PD) erythrocytes exhibited a decrease in their deformability as compared to control subjects whereas this parameter in RBC deriving from hemodialysed patients (HD) was not altered. The alleviating effect of plasma components on deformability of erythrocytes was confirmed after the isolation of a pure faction of these cells as the parameter became worse. The activity of studied enzymes: acetylcholinesterase (Ache), dehydrogenase glucose-6-phosphate (G-6-PD) and glutathione reductase (GR) maintained their physiological values in both dialysis groups.
Authors:
Ewa Nowak-Piszczek; Grazyna Wyrwicz; Zbigniew Dabrowski; Olgierd Smoleński; Krzysztof Spodaryk
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Clinical hemorheology and microcirculation     Volume:  28     ISSN:  1386-0291     ISO Abbreviation:  Clin. Hemorheol. Microcirc.     Publication Date:  2003  
Date Detail:
Created Date:  2003-08-04     Completed Date:  2004-05-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9709206     Medline TA:  Clin Hemorheol Microcirc     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  251-7     Citation Subset:  IM    
Affiliation:
Department of Hematology and Toxicology, Institute of Zoology, Jagiellonian University, Ingardena 6, 30-060 Cracow, Poland.
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MeSH Terms
Descriptor/Qualifier:
Acetylcholinesterase / metabolism
Case-Control Studies
Erythrocyte Deformability*
Erythrocytes / enzymology*
Glucosephosphate Dehydrogenase / metabolism
Glutathione Reductase / metabolism
Humans
Kidney Failure, Chronic / blood,  therapy*
Peritoneal Dialysis / adverse effects*
Renal Dialysis / adverse effects*
Chemical
Reg. No./Substance:
EC 1.1.1.49/Glucosephosphate Dehydrogenase; EC 1.8.1.7/Glutathione Reductase; EC 3.1.1.7/Acetylcholinesterase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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