| Defocused diode laser therapy (830 nm) in the treatment of unresponsive skin ulcers: a preliminary trial. | |
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MedLine Citation:
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PMID: 15204000 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Skin ulcers with compromised healing remain a major problem for plastic and dermatological surgeons. Low incident levels of laser energy have been shown to increase the blood flow rate and volume and to accelerate the wound healing process, thus raising the possibility in augmenting treatment for skin ulcers. METHODS: Preliminary controlled experiments with a 830 nm GaAlAs diode laser in axial pattern flap survival in the rat model showed statistically significant improvement in survival for the irradiated versus unirradiated control animals. In the present study, a newly developed defocused GaAlAs diode laser (830 nm, continuous wave, 669 mW/cm(2)) was applied once or twice per week in an uncontrolled study of five patients (aged between 5 and 81 years old, average 46.6 years old, doses from 6.3 J/cm(2) to 21 J/cm(2)) with previously unresponsive ulcers of various aetiologies. RESULTS: In all five patients, the ulcers healed completely between 3 weeks and 7 months (22.8 +/- 19.3 weeks), without recurrence during a minimum 12-month follow-up. CONCLUSIONS: Defocused 830 nm diode laser therapy was well tolerated, and was very effective in the treatment of this small number of compromised skin ulcers of different aetiologies and in a large range of patient ages. Further controlled studies in larger populations are required. Defocused diode laser therapy nonetheless appears to be a very useful adjunctive method in the treatment of slow-to-heal and non-healing skin ulcers. |
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Authors:
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Junichiro Kubota |
Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology Volume: 6 ISSN: 1476-4172 ISO Abbreviation: J Cosmet Laser Ther Publication Date: 2004 Jun |
Date Detail:
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Created Date: 2004-06-18 Completed Date: 2004-10-14 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 101136419 Medline TA: J Cosmet Laser Ther Country: England |
Other Details:
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Languages: eng Pagination: 96-102 Citation Subset: IM |
Affiliation:
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Japan Phototherapy Laboratory, Seiko Sunshine Building XI, 1-9-1 Higashi Ikebukuro, Toshima-ku, Tokyo 170-0013, Japan. junk@clinic-itc.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Aged Aged, 80 and over Child, Preschool Female Humans Laser Therapy, Low-Level / methods* Male Middle Aged Skin Ulcer / radiotherapy* Treatment Outcome Wound Healing / radiation effects* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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