Document Detail


Definition of cardiac structures using computerized tomography in isolated arrested and beating canine hearts.
MedLine Citation:
PMID:  855796     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Computerized axial tomography of the brain is a revolutionary noninvasive technique that has provided remarkable resolution of intracerebral structures. This study was undertaken to determine the potential of computerized tomography for defining the anatomy of 40 arrested and 9 beating (ejecting left heart preparation) canine hearts. Using an EMI cranial unit, scanning was performed in hearts under in vitro conditions with a lactated Ringer's interface. The tomographic scans obtained were later compared with comparable 8 mm thick sections of the heart. At physiologic levels of hematocrit (range 36 to 45%) external structures were well defined, but because of the lack of a differential between cavitary and myocardial densities, it was not possible to distinguish intracardiac structures. With very small amounts of iodinated contrast material (remotely administered in the case of the beating hearts) or with anemia (hematocrit less than 33%), the right and left ventricular cavities became clearly visible in both horizontal and longitudinal tomographic scans. It was possible to distinguish readily the boundaries of the ventricular and atrial cavities, the papillary muscles, the major trabeculae and the aorta. Rhythmic motion of the beating heart, suspended in its pericardium, did not eliminate structural definition. Thus, computerized tomography provides a new approach to the definition of cardiac structure with a relatively high degree of resolution. These observations point to the potential usefulness of this noninvasive technique for the evluation of both cardiac function and ventricular wall abnormalities.
Authors:
W J Powell; J Wittenberg; R E Dinsmore; S W Miller; R A Maturi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  39     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1977 May 
Date Detail:
Created Date:  1977-06-11     Completed Date:  1977-06-11     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  690-6     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Anemia
Animals
Dogs
Evaluation Studies as Topic
Heart / radiography*
Hematocrit
Tomography, X-Ray Computed*

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