Document Detail

Defining a significant stenosis in an autologous radio-cephalic arteriovenous fistula for hemodialysis.
MedLine Citation:
PMID:  21517992     Owner:  NLM     Status:  In-Data-Review    
The current definition of a significant stenosis in an autologous arteriovenous fistula (aAVF), the percentage narrowing compared with the adjacent "normal" vessel, is inaccurate. We believe a significant stenosis in the aAVF is an absolute minimal luminal diameter determined by the requirements of the hemodialysis pump. To determine what absolute diameter constitutes a hemodynamically significant stenosis in a radio-cephalic autologous arteriovenous fistula (RC aAVF), the minimal luminal diameter of dysfunctional RC aAVF was compared to that of functional RC aAVF using grayscale and color ultrasound. There were 93 fistulas in study group and 77 in control group. The mean minimum luminal diameter in study group was significantly lower than in control group (2.19 vs. 4.71 mm, p 0.001). With a cutoff value of 2.7 mm, there was 90% sensitivity and 80% specificity in distinguishing functional fistula from dysfunctional fistula. The area under the receiver-operator curve was 90% (CI 84-94%), indicating that a 2.7 mm diameter is accurate in discriminating functional from dysfunctional fistulas. An absolute minimal luminal diameter of 2.7 mm, as determined with grayscale and color ultrasound, is a useful cutoff for defining significant stenosis in a RC aAVF.
Farzan Fahrtash; Lukas Kairaitis; Simon Gruenewald; Tim Spicer; Hannah Sidrak; John Fletcher; Richard Allen; Jan Swinnen
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Seminars in dialysis     Volume:  24     ISSN:  1525-139X     ISO Abbreviation:  Semin Dial     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-04-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8911629     Medline TA:  Semin Dial     Country:  United States    
Other Details:
Languages:  eng     Pagination:  231-8     Citation Subset:  IM    
Copyright Information:
© 2011 Wiley Periodicals, Inc.
Vascular Surgery, Westmead Hospital Department of Renal Medicine, Westmead Hospital Department of Nuclear Medicine and Ultrasound, Westmead Hospital Department of Renal Medicine, Liverpool Hospital Department of Transplant Medicine, University of Sydney, Sydney, Australia.
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