Document Detail


Defining the fetal cardiac axis between 11 + 0 and 14 + 6 weeks of gestation: experience with 100 consecutive pregnancies.
MedLine Citation:
PMID:  20814876     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
OBJECTIVE: The purpose of this study was to establish normal fetal cardiac axis values during the first and early second trimesters of pregnancy.
METHODS: This was a prospective observational cohort study in which the fetal cardiac axis was assessed during ultrasound examinations in 100 consecutive fetuses between 11 + 0 and 14 + 6 weeks of gestation. Transabdominal, and, when indicated, transvaginal, approaches were used. Intraobserver and interobserver reproducibility were calculated.
RESULTS: The cardiac axis ranged from 34.5 to 56.8° (mean (SD) 47.6 ± 5.6°) in 94 fetuses with normal cardiac anatomy. The fetal cardiac axis tended to be significantly higher in fetuses at 11 + 0 to 11 + 6 weeks of gestation than in fetuses at 12 + 0 to 14 + 6 weeks of gestation. Congenital heart defects were found in six out of 100 fetuses, four of which had abnormal cardiac axis values at 11 + 0 to 14 + 6 weeks of gestation.
CONCLUSION: Cardiac axis measurement is possible in the first and early second trimesters of pregnancy. The assessment of cardiac axis at an early gestational age may help to identify pregnancies at high risk for congenital heart defects. Copyright
Authors:
E Sinkovskaya; S Horton; E M Berkley; J K Cooper; S Indika; A Abuhamad
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology     Volume:  36     ISSN:  1469-0705     ISO Abbreviation:  Ultrasound Obstet Gynecol     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9108340     Medline TA:  Ultrasound Obstet Gynecol     Country:  England    
Other Details:
Languages:  eng     Pagination:  676-81     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 ISUOG. Published by John Wiley & Sons, Ltd.
Affiliation:
Division of Maternal-Fetal Medicine of the Department of Obstetrics & Gynecology, Eastern Virginia Medical School, Norfolk, VA 23507, USA. sinkove@evms.edu
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Comment In:
Ultrasound Obstet Gynecol. 2010 Dec;36(6):658-60   [PMID:  21108303 ]

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