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Defining the adequate arterial pressure target during septic shock: not a 'micro' issue but the microcirculation can help.
MedLine Citation:
PMID:  22047945     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
ABSTRACT: The Surviving Sepsis Campaign guidelines suggest targeting a mean arterial pressure of at least 65 mm Hg to maintain organ perfusion pressure during septic shock. However, the optimal mean arterial pressure can be higher in patients with a history of hypertension or other vascular comorbidities or in those with increased abdominal pressure. In a given individual, the adequate mean arterial pressure target can be difficult to define with the routine hemodynamic parameters (for example, cardiac output, central or mixed venous blood oxygen saturation, and urine output). Near-infrared spectroscopy and sidestream dark field imaging have emerged as promising technologies for monitoring the microcirculation at the bedside. These new methods could provide additional clues to help define the adequate blood pressure to target during the resuscitation phase of septic shock.
Authors:
Serena Silva; Jean-Louis Teboul
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Publication Detail:
Type:  EDITORIAL     Date:  2011-11-2
Journal Detail:
Title:  Critical care (London, England)     Volume:  15     ISSN:  1466-609X     ISO Abbreviation:  -     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9801902     Medline TA:  Crit Care     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1004     Citation Subset:  -    
Affiliation:
AP-HP, Hôpitaux universitaires Paris-Sud, Hôpital de Bicêtre, Service de réanimation médicale, 78, rue du Général Leclerc, Le Kremlin-Bicêtre, F-94270 France. jean-louis.teboul@bct.aphp.fr.
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