Document Detail

Deficit symptoms in schizophrenia: negative symptoms versus neuroleptic-induced deficits.
MedLine Citation:
PMID:  7914043     Owner:  NLM     Status:  MEDLINE    
Definitions of negative symptoms and deficit syndromes are reviewed in this article; rating scale criteria (the Scale for Assessment of Negative Symptoms and the Positive and Negative Syndrome Scale); Crow's type II syndrome; Carpenter's deficit syndrome; and the draft of DSM-IV. The core negative symptoms identified by these investigators also describe the neuroleptic-induced deficit syndrome (NIDS). Study designs and assessment methods to distinguish NIDS from the symptoms of schizophrenia are presented. Assessment methods include rating scales and a novel method that uses descriptive symptom vignettes. Designs include neuroleptic discontinuation studies, dose comparisons and comparison of atypical antipsychotic medicines to typical neuroleptic drugs.
N R Schooler
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Acta psychiatrica Scandinavica. Supplementum     Volume:  380     ISSN:  0065-1591     ISO Abbreviation:  Acta Psychiatr Scand Suppl     Publication Date:  1994  
Date Detail:
Created Date:  1994-09-01     Completed Date:  1994-09-01     Revised Date:  2008-02-15    
Medline Journal Info:
Nlm Unique ID:  0370365     Medline TA:  Acta Psychiatr Scand Suppl     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  21-6     Citation Subset:  IM    
University of Pittsburgh, Western Psychiatric Institute and Clinic, Pennsylvania 15213.
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MeSH Terms
Affective Symptoms / chemically induced,  diagnosis,  psychology
Antipsychotic Agents / adverse effects*,  therapeutic use
Arousal / drug effects*
Diagnosis, Differential
Neurologic Examination
Psychiatric Status Rating Scales
Schizophrenia / diagnosis,  drug therapy*
Schizophrenic Psychology*
Reg. No./Substance:
0/Antipsychotic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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