Document Detail

A deficiency in haem oxygenase-1 induces foetal growth restriction by placental vasculature defects.
MedLine Citation:
PMID:  22594519     Owner:  NLM     Status:  MEDLINE    
CONCLUSION:   Therefore, we conclude that HO-1 plays an important role in placental vasculature development and a deficiency in HO-1 may contribute to pregnancy complications, such as pre-eclampsia, spontaneous abortions and premature births.
Ronald J Wong; Hui Zhao; David K Stevenson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2012-05-28
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  101     ISSN:  1651-2227     ISO Abbreviation:  Acta Paediatr.     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-07-13     Completed Date:  2012-11-05     Revised Date:  2014-07-31    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  827-34     Citation Subset:  IM    
Copyright Information:
© 2012 The Author(s)/Acta Paediatrica © 2012 Foundation Acta Paediatrica.
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MeSH Terms
Biological Markers / metabolism
Disease Models, Animal
Fetal Growth Retardation / etiology*,  metabolism
Heme Oxygenase-1 / deficiency*,  metabolism
Placenta / blood supply*,  metabolism,  pathology
Placenta Diseases / etiology*,  metabolism,  pathology
Reg. No./Substance:
0/Biological Markers; EC Oxygenase-1

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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