Document Detail

Deficiency of IgG subclasses in mothers of infants with group B streptococcal septicemia.
MedLine Citation:
PMID:  6352515     Owner:  NLM     Status:  MEDLINE    
Serum IgG subclasses were studied in 19 mothers of infants with serious infections caused by group B streptococci (GBS) and compared with a control group of 20 mothers of healthy infants. 13 of 19 mothers showed decreased subclass levels: 10 of 19 low IgG2, 9 of 19 low IgG1 and 4 of 19 low IgG3. The levels of IgG1, IgG2 and IgG3 were significantly lower among mothers of GBS-infected infants than among the controls. Thus, there is indirect evidence that the infants were immunodeficient at birth.
V A Oxelius; V Lindén; K K Christensen; P Christensen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International archives of allergy and applied immunology     Volume:  72     ISSN:  0020-5915     ISO Abbreviation:  Int. Arch. Allergy Appl. Immunol.     Publication Date:  1983  
Date Detail:
Created Date:  1983-11-23     Completed Date:  1983-11-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0404561     Medline TA:  Int Arch Allergy Appl Immunol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  249-52     Citation Subset:  IM    
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MeSH Terms
Dysgammaglobulinemia / congenital*,  immunology
IgG Deficiency*
Immunoglobulin G / classification
Infant, Newborn
Streptococcal Infections / genetics*
Streptococcus agalactiae
Reg. No./Substance:
0/Immunoglobulin G

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