Document Detail

Defensive reflexes of the respiratory system in anaesthetized rabbits during high frequency jet ventilation.
MedLine Citation:
PMID:  7873164     Owner:  NLM     Status:  MEDLINE    
The defensive airway reflexes during high frequency jet ventilation (HFJV) were studied in anaesthetized, non-vagotomized (n = 16) and vagotomized (n = 11) rabbits. The animals were ventilated by a high frequency jet ventilator. Sneezing and coughing were evoked by mechanical stimulation of the airways. During HFJV spontaneous breathing was inhibited only in the non-vagotomized rabbits. Mechanical stimulation of the airways during HFJV evoked sneezing and coughing, in which the inspiratory component was inhibited. This inhibition occurred not only in defensive reflexes evoked from the regions with increased pressure (trachea, bronchi), but also from the nose. Vagotomy diminished but did not fully eliminate the changes in sneezing accompanying HFJV. The intensity of maximum expiratory efforts was not significantly affected by HFJV in both subgroups.
K Javorka; V Kulisek; A Calkovská
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Experimental physiology     Volume:  79     ISSN:  0958-0670     ISO Abbreviation:  Exp. Physiol.     Publication Date:  1994 Nov 
Date Detail:
Created Date:  1995-04-06     Completed Date:  1995-04-06     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9002940     Medline TA:  Exp Physiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  967-73     Citation Subset:  IM    
Department of Physiology, Jessenius Medical Faculty, Comenius University, Martin, Slovakia.
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MeSH Terms
Blood Pressure / physiology
Bronchi / physiology
Cough / physiopathology
High-Frequency Jet Ventilation*
Physical Stimulation
Reflex / physiology*
Respiratory Physiological Phenomena*
Sneezing / physiology
Trachea / physiology
Vagus Nerve / physiology,  surgery

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