Document Detail

Deepening of lid sulcus from topical bimatoprost therapy.
MedLine Citation:
PMID:  15300114     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To report a new adverse effect related to treatment with bimatoprost. CASE REPORTS: Serial clinical examination of three patients was performed. In each of the three reported patients, alteration of eyelid appearance with deepening of the lid sulcus was evident as the result of topical bimatoprost therapy. DISCUSSION: A comprehensive literature search of Medline using WebMd and MDConsult, was conducted to cross reference known side effects of topical prostaglandin analog treatment. The keywords utilized were prostaglandin analogs, prostaglandins, prostamide, glaucoma, ocular hypertension, intraocular pressure, side effects, adverse effects, bimatoprost, latanoprost, lumigan, and xalatan. This appears to be the first such report in the literature. Clinicians and patients should be made aware of this possible complication of topical bimatoprost therapy.
Lee S Peplinski; Karen Albiani Smith
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Optometry and vision science : official publication of the American Academy of Optometry     Volume:  81     ISSN:  1040-5488     ISO Abbreviation:  Optom Vis Sci     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2004-08-09     Completed Date:  2004-11-16     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8904931     Medline TA:  Optom Vis Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  574-7     Citation Subset:  IM    
Bennett & Bloom Eye Centers, 4010 Dupont Circle, Suite 380, Louisville, KY 40207, USA.
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MeSH Terms
Administration, Topical
Aged, 80 and over
Antihypertensive Agents / adverse effects*
Cloprostenol / analogs & derivatives
Eyelid Diseases / chemically induced*
Glaucoma / drug therapy
Intraocular Pressure / drug effects
Lipids / adverse effects*
Middle Aged
Ophthalmic Solutions / adverse effects
Reg. No./Substance:
0/Amides; 0/Antihypertensive Agents; 0/Lipids; 0/Ophthalmic Solutions; 0/bimatoprost; 40665-92-7/Cloprostenol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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