Document Detail


Deep venous thrombosis in a patient with Behçet's disease and homozygous prothrombin (factor II) G20210A mutation on oral contraceptive pills.
MedLine Citation:
PMID:  16189654     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Behçet's disease (BD) is a multisystemic disease of unknown aetiology characterized by chronic relapsing oral aphthous lesions, genital ulcers, uveitis, and vasculopathy of both arteries and veins of all sizes. We present the case of a female patient, with BD on oral contraceptive pills, who sustained deep venous thrombosis of the long saphenous vein. The patient was found to be a carrier of a homozygous mutation of the prothrombin (factor II) G20210A gene. Our case suggests that a thrombophilia work-up may be warranted in BD patients, especially young women before they are prescribed oral contraceptives.
Authors:
Imad Uthman; Zaher Otrock; Ali Taher
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2005-09-28
Journal Detail:
Title:  Rheumatology international     Volume:  26     ISSN:  0172-8172     ISO Abbreviation:  Rheumatol. Int.     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-05-10     Completed Date:  2006-12-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8206885     Medline TA:  Rheumatol Int     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  758-9     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, Faculty of Medicine, American University of Beirut Medical Center, 113-6044, Beirut, Lebanon. iuthman@aub.edu.lb
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MeSH Terms
Descriptor/Qualifier:
Adult
Behcet Syndrome / genetics*
Contraceptives, Oral / adverse effects*
Female
Homozygote
Humans
Mutation*
Prothrombin / genetics*
Venous Thrombosis / genetics*
Chemical
Reg. No./Substance:
0/Contraceptives, Oral; 9001-26-7/Prothrombin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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