Document Detail


Deep venous thrombosis: gradient-recalled-echo MR imaging changes over time--experience in 10 patients.
MedLine Citation:
PMID:  9722839     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To determine the gradient-recalled-echo (GRE) magnetic resonance (MR) imaging changes caused by intraluminal thrombus of the lower extremities over time and to establish GRE MR imaging criteria to help distinguish acute from previous deep venous thrombosis. MATERIALS AND METHODS: Four women and six men, aged 38-76 years, underwent GRE MR imaging two to four time after the original diagnosis of deep venous thrombosis; eight also underwent confirmatory ultrasonography at that time. Follow-up was 3 months to 1 1/2 years. All patients were treated with anticoagulants. Evidence of thrombus, signal intensity characteristics, and MR imaging appearance were evaluated. RESULTS: Acute thrombosis was identified as an occlusion or prominent filling defect within the vessel. The luminal diameter of thrombosed veins was equal to or larger than that of a corresponding, unaffected vessel in each case. Acute thrombus signal intensity tended to be decreased initially and increase over time. Residual changes due to thrombosis included the web formation (n = 3), luminal narrowing (n = 4), and wall thickening and/or slow flow (n = 5). Vessels in three patients reverted to normal. CONCLUSION: GRE MR imaging demonstrated progressive changes of venous thrombus over time. These criteria may help distinguish acute deep venous thrombosis from the residual changes of previous thrombosis.
Authors:
C E Spritzer; P Trotter; H D Sostman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Radiology     Volume:  208     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1998 Sep 
Date Detail:
Created Date:  1998-09-14     Completed Date:  1998-09-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  631-9     Citation Subset:  AIM; IM    
Affiliation:
Department of Radiology, Duke University Medical Center, Durham, NC 27710, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Anticoagulants / therapeutic use
Echo-Planar Imaging / instrumentation*
Female
Follow-Up Studies
Humans
Image Enhancement / instrumentation*
Leg / blood supply
Magnetic Resonance Imaging / instrumentation*
Male
Middle Aged
Postphlebitic Syndrome / diagnosis
Thrombophlebitis / diagnosis*,  drug therapy
Treatment Outcome
Veins / pathology
Chemical
Reg. No./Substance:
0/Anticoagulants

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