Document Detail


Deep venous thrombosis associated with acute hematogenous osteomyelitis in children.
MedLine Citation:
PMID:  20833120     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: Deep venous thrombosis (DVT) is rare in children. It may complicate acute hematogenous osteomyelitis (AHO).
OBJECTIVE: The present study assessed the incidence of DVT in community-acquired AHO, and compared clinical and laboratory characteristics with AHO without DVT.
PATIENTS AND METHODS: A prospective study included patients treated for community-acquired AHO between April 2007 and December 2009.
RESULTS: Seventy patients were included: mean age, 7.7 years. Seven developed DVT. All involved Staphylococcus aureus. The isolated Staphylococcus aureus was significantly more often methicillin-resistant than methicillin-susceptible (p=0.04). C-reactive protein, erythrocyte sedimentation rate, positive blood culture and incidence of pulmonary staphylococcus were significantly higher in patients with DVT. These patients also had significantly more febrile days. One patient with DVT died from severe refractory respiratory failure.
DISCUSSION: DVT was observed in 10% of cases of community-acquired AHO. DVT was associated with more severe onset, with extensive local disease. Surgery was often needed to drain a subperiosteal abscess. DVT can cause invasive and life-threatening infection through septic emboli, particularly to the lungs.
LEVEL OF EVIDENCE: Level III.
Authors:
S Bouchoucha; F Benghachame; M Trifa; W Saied; W Douira; M N Nessib; M B Ghachem
Publication Detail:
Type:  Journal Article     Date:  2010-09-15
Journal Detail:
Title:  Orthopaedics & traumatology, surgery & research : OTSR     Volume:  96     ISSN:  1877-0568     ISO Abbreviation:  Orthop Traumatol Surg Res     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2011-03-17     Completed Date:  2011-07-27     Revised Date:  2013-10-31    
Medline Journal Info:
Nlm Unique ID:  101494830     Medline TA:  Orthop Traumatol Surg Res     Country:  France    
Other Details:
Languages:  eng     Pagination:  890-3     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Masson SAS. All rights reserved.
Affiliation:
Pediatric Orthopaedics Department, Tunis Children's Hospital, place Bab Saadoun, 1007 Tunis Jabbari, Tunisia. sami.bouchoucha@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Abscess / diagnosis,  epidemiology,  surgery
Acute Disease
Adolescent
Child
Child, Preschool
Community-Acquired Infections / diagnosis*,  epidemiology,  surgery
Cross-Sectional Studies
Diagnostic Imaging
Drainage
Female
Humans
Incidence
Infant
Male
Methicillin-Resistant Staphylococcus aureus*
Osteomyelitis / diagnosis*,  epidemiology,  surgery
Prospective Studies
Sepsis / diagnosis*,  epidemiology,  surgery
Staphylococcal Infections / diagnosis*,  epidemiology,  surgery
Venous Thrombosis / diagnosis*,  epidemiology,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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