Document Detail

Deep vein thrombosis, pulmonary embolism, and the white clot syndrome.
MedLine Citation:
PMID:  8857804     Owner:  NLM     Status:  MEDLINE    
Thromboembolic events such as deep vein thrombosis (DVT) and pulmonary embolism (PE) are very uncommon in the pediatric age group; even more rare is the white clot syndrome. We present the case of a 13-year-old girl who presented with no known risk factors for thromboembolic disease or cardiopulmonary complaints, yet was found to have extensive lower extremity DVT and PE. This patient also suffered the rare but potentially devastating complication of heparin therapy referred to as the white clot syndrome, resulting in amputation of the lower extremity. Greater awareness of both thromboembolic disease in children and the white clot syndrome may lessen the morbidity and mortality associated with these entities.
S W Melanson; B Silver; M B Heller
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American journal of emergency medicine     Volume:  14     ISSN:  0735-6757     ISO Abbreviation:  Am J Emerg Med     Publication Date:  1996 Oct 
Date Detail:
Created Date:  1996-11-13     Completed Date:  1996-11-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8309942     Medline TA:  Am J Emerg Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  558-60     Citation Subset:  IM    
Department of Emergency Medicine, St. Luke's Hospital, Bethlehem, PA 18015, USA.
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MeSH Terms
Anticoagulants / adverse effects*,  therapeutic use
Heparin / adverse effects*,  therapeutic use
Popliteal Artery*
Pulmonary Embolism / complications*,  drug therapy
Thrombophlebitis / complications*,  drug therapy
Thrombosis / chemically induced*,  complications,  surgery
Reg. No./Substance:
0/Anticoagulants; 9005-49-6/Heparin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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