| Deep vein thrombosis after total hip arthroplasty in Indian patients with and without enoxaparin. | |
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MedLine Citation:
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PMID: 15621902 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To study the incidence of deep vein thrombosis in Indian patients undergoing total hip arthroplasty with or without prophylaxis, and the effect of enoxaparin on deep vein thrombosis. METHODS: The study covered a total of 50 hips in 40 patients who underwent total hip arthroplasty. Patients were assessed for deep vein thrombosis using Doppler ultrasonography. The hips were numbered and divided into 2 groups: the odd-numbered hips did not receive any thrombo-prophylaxis, whereas the even-numbered hips received 40 mg of enoxaparin subcutaneously, once a day for 2 weeks, until the time of discharge. RESULTS: Deep vein thrombosis was not found in both groups. We found wound haematomas in 9 patients (all of whom were on enoxaparin) (p<0.05), superficial infection in 2 patients (one on enoxaparin, one not), and local bruising in 4 patients (all of whom were on enoxaparin). Major haemorrhage did not occur in any of the cases. CONCLUSION: The incidence of deep vein thrombosis in Indian patients is very low compared to that in European and American patients. Enoxaparin failed to provide any advantage to the patients. It is therefore not advisable to give prophylaxis/low-molecular-weight heparin for deep vein thrombosis to patients undergoing total hip arthroplasty without any risk factors. |
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Authors:
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V Jain; A K Dhal; B K Dhaon; G Pradhan |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of orthopaedic surgery (Hong Kong) Volume: 12 ISSN: 1022-5536 ISO Abbreviation: J Orthop Surg (Hong Kong) Publication Date: 2004 Dec |
Date Detail:
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Created Date: 2004-12-28 Completed Date: 2005-06-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9440382 Medline TA: J Orthop Surg (Hong Kong) Country: China |
Other Details:
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Languages: eng Pagination: 173-7 Citation Subset: IM |
Affiliation:
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Department of Orthopaedics and Radiodiagnosis, L.N. Hospital, New Delhi, India. vineet_leo@indiatimes.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anticoagulants / therapeutic use* Arthroplasty, Replacement, Hip / adverse effects* Enoxaparin / therapeutic use* Female Humans Incidence India / epidemiology Male Middle Aged Risk Factors Treatment Outcome Ultrasonography, Doppler Venous Thrombosis / epidemiology, etiology, prevention & control*, ultrasonography |
| Chemical | |
Reg. No./Substance:
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0/Anticoagulants; 0/Enoxaparin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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