| Deep Skin Infection of Scedosporium apiospermum in a Patient with Refractory Idiopathic Thrombocytopenic Purpura. | |
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MedLine Citation:
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PMID: 21673473 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Infection of Scedosporium apiospermum is very rare but is now emerging as an important cause of both localized and disseminated infections in immunocompromised patients. A 62-year-old woman, who had undergone steroid therapy for refractory idiopathic thrombocytopenic purpura and had a history of diffuse large B cell lymphoma, developed a deep skin ulcer complicated with lymphangitis. After culture study demonstrated the presence of S. apiospermum, voriconazole (VRCZ) was administered and prompt improvement was observed. Because it is difficult to distinguish S. apiospermum from Aspergillus by histopathology and S. apiospermum is resistant to amphotericin B, VRCZ should be selected as the first choice of antifungal agent when mold is considered to be the causative organism. |
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Authors:
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Makoto Takeuchi; Chikamasa Yoshida; Yusuke Ota; Yutaka Fujiwara |
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Publication Detail:
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Type: Journal Article Date: 2011-06-15 |
Journal Detail:
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Title: Internal medicine (Tokyo, Japan) Volume: 50 ISSN: 1349-7235 ISO Abbreviation: Intern. Med. Publication Date: 2011 |
Date Detail:
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Created Date: 2011-06-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9204241 Medline TA: Intern Med Country: Japan |
Other Details:
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Languages: eng Pagination: 1339-43 Citation Subset: IM |
Affiliation:
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Division of Hematology, National Hospital Organization Minami-Okayama Medical Center, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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