| Deep Medullary Veins Involvement in Neonates with Brain Damage: An MR Imaging Study. | |
| | |
MedLine Citation:
|
PMID: 21960491 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
BACKGROUND AND PURPOSE:Different and specific MR imaging patterns of lesions involving WM are widely defined in neonatal encephalopathy. The aim of this study was to describe a novel MR imaging pattern of damage characterized by the abnormal prominence of DMVs in premature and full-term neonates.MATERIALS AND METHODS:Twenty-one (11 premature and 10 full-term) neonates with MR imaging evidence of linear radially oriented fan-shaped lesions in the periventricular WM and without dural venous thrombosis were enrolled in this retrospective study. A total of 37 MR imaging examinations were performed at ages ranging from day 0 to 24 months.RESULTS:According to the appearance of linear anomalies on T2-weighted images, we identified 2 main patterns: T2 hypointense lesions without WM cavitations and T2 hypointense lesions associated with linear cysts. The first pattern was found in 17 examinations performed between 0 and 44 days of life; the second pattern was found in another 14 examinations performed between 6 days and 4 months of life. Five examinations performed between 9 and 24 months of life showed a reduction in volume and hyperintense signal intensity of the periventricular WM on T2-weighted and FLAIR images.CONCLUSIONS:Subtle linear WM lesions with the same anatomic distribution of DMVs may be evident in premature and full-term neonates without signs of major venous thrombosis, both in the acute and subacute phases. Their appearance and evolution suggest that transient DMV engorgement/thrombosis may be responsible for WM damage that can lead to a PVL-like pattern. |
| | |
Authors:
|
F Arrigoni; C Parazzini; A Righini; C Doneda; L A Ramenghi; G Lista; F Triulzi |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-9-29 |
Journal Detail:
|
Title: AJNR. American journal of neuroradiology Volume: - ISSN: 1936-959X ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
|
Created Date: 2011-9-30 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8003708 Medline TA: AJNR Am J Neuroradiol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Departments of Radiology and Neuroradiology, Children's Hospital V. Buzzi-Instituti Clinic di Perfezionamento, Milan, Italy; Neonatal Intensive Care Unit, Children's Hospital V. Buzzi-ICP, Milan, Italy; Neonatal Intensive Care Unit, Fondazion IRCCS Ca'Granda-Ospedale Maggiore Policlinico, Milan, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The Use of Onyx in Different Types of Intracranial Dural Arteriovenous Fistula.
Next Document: Erdheim-Chester Disease of the Central Nervous System: New Manifestations of a Rare Disease.