| Dedifferentiation phenomena after denervation of mammalian adult vestibular receptors. | |
| | |
MedLine Citation:
|
PMID: 1751803 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The effect of transecting the vestibular nerve on the vestibular sensory epithelium was studied in adult guinea-pigs. When denervation was complete, after fifteen days, the vestibular hair cells began to show morphological features of immaturity. After two months, the majority of hair cells showed a supporting cell phenotype. By four months, both hair cells and supporting cells had become morphologically similar to the epithelial cells which line the vestibular cavities. When denervation was incomplete, hair cells and supporting cells retained their normal phenotype. This, plus the dedifferentiation after complete denervation, indicates that the phenotypes of the hair cells and supporting cells are innervation-dependent. |
| | |
Authors:
|
D Favre; A Sans |
Related Documents
:
|
21105933 - Ethylene directs auxin to control root cell expansion. 17823553 - Aminoglycoside ototoxicity. 19330883 - The extent of phase i and phase ii reactions is affected by the choice of enzyme used t... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Neuroreport Volume: 2 ISSN: 0959-4965 ISO Abbreviation: Neuroreport Publication Date: 1991 Sep |
Date Detail:
|
Created Date: 1992-01-27 Completed Date: 1992-01-27 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 9100935 Medline TA: Neuroreport Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 501-4 Citation Subset: IM; S |
Affiliation:
|
INSERM-U254, Laboratoire de Neurophysiologie sensorielle, Université de Montepellier, France. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Age Factors Animals Cell Differentiation Denervation Epithelium / pathology Guinea Pigs Hair Cells, Auditory / pathology* Phenotype Vestibular Nerve / injuries* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Design of new anti-viral agents for chronic hepatitis B virus infection.
Next Document: Embryonic mouse spinal cord motor neuron hybrid cells.