Document Detail

Decreasing profile of residual sulphaquinoxaline in eggs.
MedLine Citation:
PMID:  9649878     Owner:  NLM     Status:  MEDLINE    
1. Sulphaquinoxaline (SQ) was added to the diet of laying hens at 200 mg/kg for 7 successive days. Contents (mg/kg) of SQ in albumen and egg yolk of eggs laid after drug withdrawal were determined by high pressure liquid chromatography (HPLC). The contents in the whole egg were calculated taking into consideration the respective weights of albumen and egg yolk. 2. A time-lag in the initiation of decrease of SQ from eggs after the withdrawal of dietary SQ was observed. 3. The decreasing pattern from whole egg could be well described by the following equation with a time-lag of 1.0 d, y = 2.07 e-0.5620(t-1.0), where y is the SQ content in whole egg, t is time (d) after the withdrawal of dietary SQ and a constant of 2.07 is the SQ content in whole egg laid at the withdrawal. 4. Biological half-life of SQ in the whole egg was estimated to be 1.23 d. 5. From the above equation, SQ residue of whole egg laid at 9th d after withdrawal will be below the detection limit of 0.01 mg/kg.
N Furusawa; Y Tsuzukida; H Yamaguchi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British poultry science     Volume:  39     ISSN:  0007-1668     ISO Abbreviation:  Br. Poult. Sci.     Publication Date:  1998 May 
Date Detail:
Created Date:  1998-09-16     Completed Date:  1998-09-16     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  15740290R     Medline TA:  Br Poult Sci     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  241-4     Citation Subset:  IM    
Faculty of Human Life Science, Osaka City University, Japan.
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MeSH Terms
Animal Feed
Anti-Infective Agents / administration & dosage,  analysis*,  pharmacokinetics
Chromatography, High Pressure Liquid
Drug Residues / analysis*
Egg White / analysis
Egg Yolk / chemistry
Eggs / analysis*
Sulfaquinoxaline / administration & dosage,  analogs & derivatives,  analysis*,  pharmacokinetics
Time Factors
Reg. No./Substance:
0/Anti-Infective Agents; 59-40-5/Sulfaquinoxaline

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