Document Detail

Decreasing blood donor exposure in the neonates by using dedicated donor transfusions.
MedLine Citation:
PMID:  10174685     Owner:  NLM     Status:  MEDLINE    
Critically ill infants receive frequent red cell transfusions for replacement of blood drawn for laboratory analysis and in treatment of symptomatic anemia. Since blood for multiple transfusions on a given day is typically obtained from one fresh RBC unit, each multiply transfused neonate is exposed to many donors increasing the risk of transfusion transmitted disease. We hypothesized that the number of donor exposures per infant would decrease by instituting DDTP and that more infants will be exposed to only a single donor. We started a Dedicated Donor Transfusion Program (DDTP) in our NICU. One unit of red cells is dedicated to each baby for the life of the unit (35 days). We compared the donor exposure in infants for one year, before and after DDTP. The infants were divided into three birth weight groups. Group I were infants < 1000 g; Group II infants were 1000-1500 g; Group III infants were > 1500g. The average number of transfusions per patient decreased significantly from 7.5 +/- 6.0 to 4.7 +/- 4.2 (P < 0.001) in Group I while it remained unchanged in Groups II and III. The Dedicated Donor Transfusion Program significantly reduced the donor exposure in NICU infants. The program also facilitated the reduction of the number of transfusions in the infants under 1000 g.
R Jain; C R Jarosz; T F Myers
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Transfusion science     Volume:  18     ISSN:  0955-3886     ISO Abbreviation:  Transfus Sci     Publication Date:  1997 Jun 
Date Detail:
Created Date:  1998-01-14     Completed Date:  1998-01-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9001514     Medline TA:  Transfus Sci     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  199-203     Citation Subset:  T    
Department of Pediatrics, Loyola University Medical Center, Maywood, IL 60153, USA.
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MeSH Terms
Blood Donors*
Blood Transfusion / adverse effects*
Infant, Newborn
Infant, Very Low Birth Weight*

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