Document Detail

Decreased serum alpha-amylase levels in infected Nigerian newborn infants.
MedLine Citation:
PMID:  3259437     Owner:  NLM     Status:  MEDLINE    
Serum alpha-amylase activity was determined in 41 newborn infants with proven bacterial infections and compared to values obtained in 18 healthy control neonates. In the infected neonates serum alpha-amylase value, as determined by the blue starch method, was only 40% that of healthy controls; the mean value of 175.1 +/- 64.9 IU/l for healthy neonates was significantly higher (p less than 0.0010) than the value of 82.8 +/- 44.4 IU/l for the infected neonates. Alpha-amylase levels did not correlate with severity of infections or mortality. The sensitivity and specificity of serum alpha-amylase level of 100 IU/l were 75.6 and 94.7%; the positive and negative predictive values were 91.2 and 84.4%, respectively.
A A Okolo; A Okorodudu; R H Glew; J A Omene
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Biology of the neonate     Volume:  53     ISSN:  0006-3126     ISO Abbreviation:  Biol. Neonate     Publication Date:  1988  
Date Detail:
Created Date:  1988-06-24     Completed Date:  1988-06-24     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0247551     Medline TA:  Biol Neonate     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  138-43     Citation Subset:  IM    
Department of Child Health, College of Medical Sciences, University of Benin, Nigeria.
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MeSH Terms
Infant Nutritional Physiological Phenomena
Infant, Newborn / blood*,  physiology
Infant, Newborn, Diseases / blood*,  enzymology,  physiopathology
alpha-Amylases / blood*
Reg. No./Substance:

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