Document Detail

Decreased pregnancy rate after in-vitro fertilization in HIV-infected women receiving HAART.
MedLine Citation:
PMID:  16327329     Owner:  NLM     Status:  MEDLINE    
A study on in-vitro fertilization (IVF) was conducted among HIV-infected women. In these patients, a reduced pregnancy rate after IVF was observed if the patient's own oocytes were used. However, no significant reduction in the pregnancy rate was found if donated oocytes were used. The CD4 lymphocyte count was independently associated with ovarian resistance to hyperstimulation. Subclinical hypogonadism mediated by immunosuppression may explain these observations, suggesting the need to optimize the immunological status of the patient before considering assisted reproduction treatments.
Oriol Coll; Anna Suy; Francesc Figueras; Valérie Vernaeve; Esteban Martínez; Daniel Mataró; Mercè Durban; Montserrat Lonca; Ricard Vidal; José María Gatell
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  AIDS (London, England)     Volume:  20     ISSN:  0269-9370     ISO Abbreviation:  AIDS     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2005-12-05     Completed Date:  2006-06-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8710219     Medline TA:  AIDS     Country:  England    
Other Details:
Languages:  eng     Pagination:  121-3     Citation Subset:  IM; X    
Clinica Eugin, IDIBAPS, University of Barcelona, Barcelona, Spain.
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MeSH Terms
Antiretroviral Therapy, Highly Active / adverse effects*
CD4 Lymphocyte Count
Cohort Studies
Fertilization in Vitro*
Follicle Stimulating Hormone / analysis
HIV Infections / drug therapy*,  immunology
Oocytes / immunology
Ovary / immunology
Pregnancy Complications, Infectious / immunology
Reg. No./Substance:
9002-68-0/Follicle Stimulating Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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