| Decreased plasma pancreatic polypeptide levels in pregnancy. | |
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MedLine Citation:
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PMID: 7204535 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The pancreatic polypeptide (PP) response to oral glucose ingestion was determined in late pregnancy and post partum in 11 normal healthy women. Glucose tolerance was significantly impaired in pregnancy compared to post partum. Fasting plasma PP concentrations were reduced in pregnancy [7.6 +/- 1.2 vs. 12.6 +/- 1.2 pmol liter-1 (mean +/0- SE); P less than 0.01]. The levels of PP increased after glucose ingestion during pregnancy as well as post partum, but the PP response was significantly impaired in gestation (integrated PP responses: 548 +/- 331 vs. 1645 +/- 347 pmol liter-1 min-1; P less than 0.01). It is concluded that in pregnancy, PP levels after an overnight fast are decreased and the PP response to glucose is diminished compared to post partum. |
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Authors:
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P J Hornnes; C Kühl |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Journal of clinical endocrinology and metabolism Volume: 52 ISSN: 0021-972X ISO Abbreviation: J. Clin. Endocrinol. Metab. Publication Date: 1981 Apr |
Date Detail:
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Created Date: 1981-05-26 Completed Date: 1981-05-26 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0375362 Medline TA: J Clin Endocrinol Metab Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 605-7 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Glucose / analysis Fasting Female Glucose / diagnostic use Humans Pancreatic Polypeptide / blood* Pregnancy* |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose; 50-99-7/Glucose; 59763-91-6/Pancreatic Polypeptide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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