Document Detail


Decreased plasma carnitine in Type I diabetes mellitus
MedLine Citation:
PMID:  1921235     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Realizing the importance of carnitine for the lipid and carbohydrate metabolism and the possible role for glucose utilization and myocardial function carnitine concentrations in type I and type II diabetic patients in plasma, erythrocytes and 24 h urine were determined. The plasma levels of carnitine were significantly diminished in type I diabetic patients compared to controls, while carnitine concentrations in erythrocytes and 24 h urine did not differ from controls. Plasma carnitine levels did not change significantly during the diurnial profile. No correlation between HbA1c and carnitine levels was observed in the diabetic patients.
Authors:
P Pregant; G Schernthaner; E Legenstein; L Lienhart; S Bruck; C Schnack; E Kaiser
Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Klinische Wochenschrift     Volume:  69     ISSN:  0023-2173     ISO Abbreviation:  Klin. Wochenschr.     Publication Date:  1991 Aug 
Date Detail:
Created Date:  1991-11-07     Completed Date:  1991-11-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985205R     Medline TA:  Klin Wochenschr     Country:  GERMANY    
Other Details:
Languages:  ger     Pagination:  511-6     Citation Subset:  IM    
Affiliation:
Institut für Medizinische Chemie, Universität Wien.
Vernacular Title:
Vermindertes Plasmacarnitin bei Typ-I Diabetes mellitus.
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Glucose / metabolism
Carnitine / blood*,  urine
Circadian Rhythm
Diabetes Mellitus, Type 1 / blood*
Diabetes Mellitus, Type 2 / blood
Erythrocytes / chemistry
Female
Hemoglobin A, Glycosylated / analysis
Humans
Lipid Metabolism
Male
Middle Aged
Chemical
Reg. No./Substance:
0/Blood Glucose; 0/Hemoglobin A, Glycosylated; 541-15-1/Carnitine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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