Document Detail

Decreased nasal mucosal sensitivity in older subjects.
MedLine Citation:
PMID:  16871945     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The sensitivity of the human nasal cavity mucosa to touch is not well understood. The site of receptors and mode of action responsible for the sensation of the nasal airflow is a topic of controversy. Previous studies have suggested that the skin-lined nasal vestibule is more sensitive to airflow than the mucosa of the nasal cavity. A possible decline in nasal sensitivity to airflow in older subjects has not been studied. METHODS: The threshold of the mucosal sensitivity to jets of air was assessed in 76 subjects with healthy nasal cavities. A total of 141 nostrils were tested, 67 in younger patients and 74 in older patients. RESULTS: Statistically significant (p < 0.001) increases in thresholds were found for all points tested for older patients compared with the younger patients. In general, the more sensitive locations were in the nasal vestibule. The nasal cavity mucosa in the inferior meatus was slightly more sensitive than the middle meatus. CONCLUSION: We have measured the threshold to touch (air jet sensitivity) in nine places in each of 141 nasal cavities and determined that the variability and sensitivity of these measurements among people varies by age and the distance from the nostril. Older subjects were found to have a higher threshold for the sensation of airflow, and the nasal vestibule was found to be more sensitive than the rest of the nasal cavity mucosa with the inferior meatus slightly more sensitive then the middle meatus.
Bozena B Wrobel; Alexander G Bien; Eric H Holbrook; George E Meyer; Neil A Bratney; Jane Meza; Donald A Leopold
Related Documents :
17516815 - Relationships between musical structure and psychophysiological measures of emotion.
9336805 - Epidermolysis bullosa associated with congenital localized absence of skin, fetal abdom...
7462435 - Neonatal spongioform myelinopathy after restricted application of hexachlorophane skin ...
20346075 - Extremely preterm infants tolerate skin-to-skin contact during the first weeks of life.
2741855 - Manganese absorption from human milk, cow's milk, and infant formulas in humans.
6291315 - Pituitary-adrenal and testicular function in preterm infants after prenatal dexamethaso...
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of rhinology     Volume:  20     ISSN:  1050-6586     ISO Abbreviation:  Am J Rhinol     Publication Date:    2006 May-Jun
Date Detail:
Created Date:  2006-07-28     Completed Date:  2006-11-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8807268     Medline TA:  Am J Rhinol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  364-8     Citation Subset:  IM    
Department of Otolaryngology-Head and Neck Surgery, University of Southern California, Los Angeles, California, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aging / physiology*
Middle Aged
Nasal Mucosa / physiology*
Sensation / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Characteristics of nasal inverted papilloma and its malignant transformation: a study of cell prolif...
Next Document:  Cisplatin, gemcitabine and paclitaxel triplet chemotherapy in 50 patients with advanced or metastati...