Document Detail


Decreased lung function and exercise capacity in Fontan patients. A long-term follow-up.
MedLine Citation:
PMID:  12745804     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The haemodynamic situation for patients with Fontan circulation is characterized by a reduced, non-pulsatile pulmonary blood flow. To evaluate if this has any impact on lung function and exercise capacity, we studied the surviving 20 patients operated upon at our institution between 1980 and 1991. The median age was 17.5 years, the median follow-up time was 11.5 years. DESIGN: Lung volumes, flow-volume curves, the ventilatory distribution and the diffusion capacity for carbon monoxide were obtained using routine methods. The exercise tests were performed on a bicycle ergometer with determination of ventilation, oxygen uptake, carbon dioxide production, respiratory rate and heart rate. RESULTS: The lung volumes, maximal expiratory flows and diffusion capacity were significantly lower than expected. The median maximal oxygen uptake was 1.39 for the females and 1.63 l/min for the males, corresponding to 25.1 and 25.2 ml/kg/min, respectively. The maximal heart rates varied from 104 to 177 beats/min. All patients reached a respiratory exchange ratio above 1.0. CONCLUSION: Fontan patients have small lungs. They have a markedly reduced exercise capacity and a low maximal heart rate.
Authors:
Eva Strömvall Larsson; Bengt O Eriksson; Rune Sixt
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Scandinavian cardiovascular journal : SCJ     Volume:  37     ISSN:  1401-7431     ISO Abbreviation:  Scand. Cardiovasc. J.     Publication Date:  2003  
Date Detail:
Created Date:  2003-05-14     Completed Date:  2003-11-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9708377     Medline TA:  Scand Cardiovasc J     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  58-63     Citation Subset:  IM    
Affiliation:
Department of Paediatric Cardiology, The Queen Silvia Children's Hospital, Göteborg University, SE-416 85 Göteborg, Sweden. eva.stromvall-larsson@vgregion.se
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Child
Child, Preschool
Exercise Test
Exercise Tolerance / physiology*
Female
Follow-Up Studies
Heart Rate / physiology
Humans
Lung / pathology,  physiopathology*,  surgery*
Lung Diseases / pathology,  physiopathology*,  surgery
Lung Volume Measurements
Male
Postoperative Complications / physiopathology
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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