Document Detail

Decreased heart rate variation in decerebration syndrome: quantitative clinical criterion of brain death?
MedLine Citation:
PMID:  704201     Owner:  NLM     Status:  MEDLINE    
Heart rate variation (HRV) was measured in 12 children with brain death. Computer analysis demonstrated an overall heart rate variation (RMSM) of 3.5 to 9.6 msec (mean, 6.0 msec). The respective figures for beat-to-beat variation (RMSSD) were 4 to 16 msec (mean, 7.7 msec). Normal infants (RMSM, 20 to 30 msec) and children (RMSM, 50 to 90 msec) and infants with respiratory distress syndrome (RMSM, 10 to 20 msec) have a clearly higher HRV than those with brain death. In all subjects a periodic component of the HRV with a cycle length of 5.9 +/- 0.26 seconds was discovered. In five patients an additional periodic component was found that corresponded exactly to the rate of artificial respiration. This study demonstrated the value of accurate digital techniques in the characterization of fixed heart rate in decerebration. This phenomenon could be considered one clinical criterion of brain death.
P Kero; K Antila; V Ylitalo; I Välimäki
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatrics     Volume:  62     ISSN:  0031-4005     ISO Abbreviation:  Pediatrics     Publication Date:  1978 Sep 
Date Detail:
Created Date:  1978-12-20     Completed Date:  1978-12-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376422     Medline TA:  Pediatrics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  307-11     Citation Subset:  AIM; IM    
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MeSH Terms
Brain Death*
Child, Preschool
Decerebrate State / physiopathology*
Heart Rate*
Infant, Newborn

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