Document Detail


Decreased fetal movement prompts investigation of prenatal/neonatal nemaline myopathy: The possible merit of fetal movement count.
MedLine Citation:
PMID:  21395907     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We highlight the merit of fetal movement count to identify a fetus with neuromuscular disorder: nemaline myopathy. A 38-year-old 1-para woman not in a consanguineous marriage had decreased fetal movement. This, together with increased amniotic fluid volume, led us to perform detailed ultrasound examinations, which revealed stretch contracture of the knee joints, leading us to suspect fetal neuromuscular disorders. At 38(2/7) , she gave birth vaginally to a 2444 g female infant. Her respiration was very weak, requiring respiratory support. Contractures of the upper/lower extremity joints and club feet were observed. All skeletal muscles were hypotonic. Biopsized muscle cells showed nemaline bodies, confirming the diagnosis of nemaline myopathy. Fetal movement count may contribute to the identification of fetal neuromuscular diseases, such as nemaline myopathy.
Authors:
Tomoyuki Kuwata; Shigeki Matsubara; Takashi Ohkusa; Yukari Yada; Mitsuaki Suzuki
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-13
Journal Detail:
Title:  The journal of obstetrics and gynaecology research     Volume:  -     ISSN:  1341-8076     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-3-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9612761     Medline TA:  J Obstet Gynaecol Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2011 The Authors. Journal of Obstetrics and Gynaecology Research © 2011 Japan Society of Obstetrics and Gynecology.
Affiliation:
Departments of Obstetrics and Gynecology and Jichi Perinatal Education CenterPediatrics, Jichi Medical University, TochigiOhkusa Ladies' Clinic, Sakura, Tochigi, Japan.
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