| Decreased carotid intima-media thickness in patients with coronary artery ectasia compared with patients with coronary artery disease. | |
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MedLine Citation:
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PMID: 16319660 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Although atherosclerosis is supposed to be responsible for more than 50% of coronary artery ectasia, the precise pathology of coronary artery ectasia is not clearly understood. A histopathological examination of ectatic segments has revealed mainly destruction of the media layer of the artery. In the present study, we assessed carotid intima-media thickness and common carotid artery diameter in patients with and without coronary artery ectasia. MATERIALS AND METHODS: Thirty-five consecutive patients with coronary artery ectasia and coronary artery disease and 35 age and sex-matched patients with coronary artery disease alone were included in the study. The common carotid artery was studied as the longitudinal plane within 10 mm from the bifurcation of the common carotid artery. The intima-media thickness was measured in the far wall at end-diastole from the B-mode screen to a point within the 10-mm segment proximal to the bifurcation by one investigator blinded to clinical data. RESULTS: No significant differences with respect to age, body mass index, hypertension, diabetes mellitus, hypercholesterolemia and smoking habits were observed between the two groups studied. Intima-media thickness of the common carotid artery of the patients with coronary artery ectasia was significantly lower than that of the patients with coronary artery disease alone (0.71 +/- 0.13 vs. 0.77 +/- 0.09 mm, respectively, P = 0.04). CONCLUSION: Decreased intima-media thickness of the carotid artery in patients with coronary artery ectasia and coronary artery disease may have pathogenic mechanisms different from coronary artery disease per se. |
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Authors:
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Ertan Yetkin; Nusret Acikgoz; Yuksel Aksoy; Emrah Bariskaner; Nasir Sivri; Erdal Akturk; Hasan Turhan; Feridun Kosar; Sengul Cehreli |
Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Coronary artery disease Volume: 16 ISSN: 0954-6928 ISO Abbreviation: Coron. Artery Dis. Publication Date: 2005 Dec |
Date Detail:
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Created Date: 2005-12-01 Completed Date: 2006-12-11 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9011445 Medline TA: Coron Artery Dis Country: England |
Other Details:
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Languages: eng Pagination: 495-8 Citation Subset: IM |
Affiliation:
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Department of Cardiology, Inonu University School of Medicine, Malatya, Turkey. eryetkin@ttnet.net.tr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Carotid Artery, Common / pathology*, ultrasonography Coronary Artery Disease / pathology*, ultrasonography Coronary Vessel Anomalies / pathology*, ultrasonography Coronary Vessels / pathology, ultrasonography Dilatation, Pathologic / pathology, ultrasonography Female Humans Male Middle Aged Tunica Intima / pathology*, ultrasonography Tunica Media / pathology*, ultrasonography |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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