Document Detail

Decreased carotid intima-media thickness in patients with coronary artery ectasia compared with patients with coronary artery disease.
MedLine Citation:
PMID:  16319660     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Although atherosclerosis is supposed to be responsible for more than 50% of coronary artery ectasia, the precise pathology of coronary artery ectasia is not clearly understood. A histopathological examination of ectatic segments has revealed mainly destruction of the media layer of the artery. In the present study, we assessed carotid intima-media thickness and common carotid artery diameter in patients with and without coronary artery ectasia. MATERIALS AND METHODS: Thirty-five consecutive patients with coronary artery ectasia and coronary artery disease and 35 age and sex-matched patients with coronary artery disease alone were included in the study. The common carotid artery was studied as the longitudinal plane within 10 mm from the bifurcation of the common carotid artery. The intima-media thickness was measured in the far wall at end-diastole from the B-mode screen to a point within the 10-mm segment proximal to the bifurcation by one investigator blinded to clinical data. RESULTS: No significant differences with respect to age, body mass index, hypertension, diabetes mellitus, hypercholesterolemia and smoking habits were observed between the two groups studied. Intima-media thickness of the common carotid artery of the patients with coronary artery ectasia was significantly lower than that of the patients with coronary artery disease alone (0.71 +/- 0.13 vs. 0.77 +/- 0.09 mm, respectively, P = 0.04). CONCLUSION: Decreased intima-media thickness of the carotid artery in patients with coronary artery ectasia and coronary artery disease may have pathogenic mechanisms different from coronary artery disease per se.
Ertan Yetkin; Nusret Acikgoz; Yuksel Aksoy; Emrah Bariskaner; Nasir Sivri; Erdal Akturk; Hasan Turhan; Feridun Kosar; Sengul Cehreli
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Coronary artery disease     Volume:  16     ISSN:  0954-6928     ISO Abbreviation:  Coron. Artery Dis.     Publication Date:  2005 Dec 
Date Detail:
Created Date:  2005-12-01     Completed Date:  2006-12-11     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9011445     Medline TA:  Coron Artery Dis     Country:  England    
Other Details:
Languages:  eng     Pagination:  495-8     Citation Subset:  IM    
Department of Cardiology, Inonu University School of Medicine, Malatya, Turkey.
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MeSH Terms
Carotid Artery, Common / pathology*,  ultrasonography
Coronary Artery Disease / pathology*,  ultrasonography
Coronary Vessel Anomalies / pathology*,  ultrasonography
Coronary Vessels / pathology,  ultrasonography
Dilatation, Pathologic / pathology,  ultrasonography
Middle Aged
Tunica Intima / pathology*,  ultrasonography
Tunica Media / pathology*,  ultrasonography

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