Document Detail


Decreased bone density in ambulatory patients with duchenne muscular dystrophy.
MedLine Citation:
PMID:  11856925     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Osteoporosis has been recognized in nonambulatory boys with Duchenne's muscular dystrophy. In this study, the hips and spines of 10 ambulatory children with Duchenne's muscular dystrophy were examined. The study group comprised 10 boys with a mean age of 8 years (range 6-11). All patients were scanned by dual-energy x-ray absorptiometry (DEXA) using a DPX LUNAR Corporation scanner (Madison, WI, U.S.A.). Manual muscle testing of the major muscle groups of the upper and lower extremities was performed on all patients. Pubertal development status was determined using the Tanner scale. Although they were still ambulatory, boys diagnosed with Duchenne's muscular dystrophy experienced weakness in the lower extremity musculature, as well as proximal femur and lumbar spine osteoporosis or osteopenia.
Authors:
Luis F Aparicio; Marguerite Jurkovic; James DeLullo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pediatric orthopedics     Volume:  22     ISSN:  0271-6798     ISO Abbreviation:  J Pediatr Orthop     Publication Date:    2002 Mar-Apr
Date Detail:
Created Date:  2002-02-21     Completed Date:  2002-05-03     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8109053     Medline TA:  J Pediatr Orthop     Country:  United States    
Other Details:
Languages:  eng     Pagination:  179-81     Citation Subset:  IM    
Affiliation:
Hamot Medical Center, Erie, Pennsylvania , USA.
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MeSH Terms
Descriptor/Qualifier:
Absorptiometry, Photon
Bone Density*
Child
Humans
Male
Muscular Dystrophy, Duchenne* / complications
Walking

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