Document Detail


Decreased arteriovenous flow resistance in the left gastric venous area in cirrhotic patients.
MedLine Citation:
PMID:  6800806     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To assess the relationship between the fluid mechanics in the left gastric venous area and the portal trunk, manometric measurements were made in patients with or without cirrhosis of the liver. In ten normal subjects, temporary portal vein occlusion produced comparable elevation in both the occluded left gastric venous pressure (OLGP) and the portal vein pressure (PVP); 152-429 mm of water in OLGP and 115-452 mm of water in PVP. In sixty cirrhotic patients, however, the portal vein occlusion resulted in far less increase in OLGP than that in PVP; 281-365 mm of water in OLGP and 281-540 mm of water in PVP. In other words, regarding pressure measurements, the relationship was 'separated' in cirrhotics, but 'continuous' in normal subjects. Mathematical analysis of the data using a modification of Wheat-stone bridge model suggested that the arteriovenous flow resistance in the left gastric venous area of cirrhotics was reduced to less than one fifth of that in the controls. It would appear that the increased flow capacity as a result of a reduced arteriovenous flow resistance is responsible for the functional 'separation' from the portal trunk.
Authors:
N Koyanagi; K Inokuchi; S Nakayama; H Sakata; K Beppu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of clinical investigation     Volume:  11     ISSN:  0014-2972     ISO Abbreviation:  Eur. J. Clin. Invest.     Publication Date:  1981 Oct 
Date Detail:
Created Date:  1982-05-12     Completed Date:  1982-05-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0245331     Medline TA:  Eur J Clin Invest     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  355-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Humans
Liver Cirrhosis / physiopathology*
Portal Vein / physiopathology
Stomach / blood supply*
Vascular Resistance*
Venous Pressure

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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