Document Detail

Decreased activity and oxygen desaturation in prone ventilated preterm infants during the first postnatal week.
MedLine Citation:
PMID:  11805748     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To compare the effects of supine and prone positions on oxygen saturation (SpO(2)), desaturation episodes (SpO(2) < 90% and >or= 20 seconds), and motor activity in ventilated preterm infants during their first postnatal week. DESIGN: With use of a crossover design, we randomly assigned infants to a supine/prone or prone/supine position sequence. Infants were placed in each position for 2 hours. A stabilization period of 10 minutes before observation of each position was allowed. During the protocol, care procedures were kept minimal and ventilator settings remained unchanged. SETTING: Neonatal intensive care units at 2 tertiary care centers in Taiwan. SAMPLE: The sample consisted of 28 infants receiving mechanical ventilation who were 25 to 36 weeks' gestation, without known congenital abnormalities, within 7 postnatal days of birth, and were not receiving sedation. RESULTS: When prone, infants had higher SpO(2), fewer episodes of oxygen desaturation, and less motor activity than when supine. No significant differences in duration of SpO(2) less than 90%, 85%, and 80% were found between the 2 positions. Seventy-four percent of desaturation episodes were associated with vigorous motor activity and crying. CONCLUSION: The prone position results in less motor activity and may stabilize oxygenation for ventilated preterm infants. This may conserve energy and decrease complications of hypoxia for sick preterm infants.
Ying-Ju Chang; Gene Cranston Anderson; Donna Dowling; Chyi-Her Lin
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Heart & lung : the journal of critical care     Volume:  31     ISSN:  0147-9563     ISO Abbreviation:  Heart Lung     Publication Date:    2002 Jan-Feb
Date Detail:
Created Date:  2002-01-23     Completed Date:  2002-03-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0330057     Medline TA:  Heart Lung     Country:  United States    
Other Details:
Languages:  eng     Pagination:  34-42     Citation Subset:  AIM; IM    
Department of Nursing, College of Medicine of National Cheng Kung University, Tainan, Taiwan, Republic of China.
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MeSH Terms
Cross-Over Studies
Infant, Newborn
Infant, Premature*
Oxygen / blood*
Prone Position*
Respiration, Artificial*
Supine Position*
Time Factors
Reg. No./Substance:

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