| Decorrelation characteristics of transverse blood flow along an intravascular array catheter: effects of aggregation of red blood cells. | |
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MedLine Citation:
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PMID: 11369127 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A method to measure transverse blood flow, based on the correlation between consecutive radiofrequency (RF) signals, has been introduced. This method was validated for an intravascular (IVUS) rotating single element catheter. Currently, we are implementing the method for an IVUS array transducer catheter. The decorrelation characteristics during transverse blood flow using the IVUS array catheter were investigated using computer modeling. Before this, blood was simulated as a collection of randomly located point scatterers and, by moving this scattering medium transversely across the acoustical beam, blood flow was simulated. This paper presents a more realistic scattering media by simulating aggregates of red blood cells (RBCs) as strings of point scatterers. Three configurations of aggregates of RBCs were simulated. First, aggregates of RBCs were strings with different lengths and parallel to the catheter axis. Second, the strings were with a fixed length and angles of plus or minus 45 degrees with respect to the catheter axis. Third, the strings were with different lengths and random angles ranging from -45 degrees to + 45 degrees. The decorrelation characteristics for these configurations of aggregates of RBCs were investigated and compared with point scatterers. For the aggregates of RBCs parallel to the catheter axis, the decorrelation rate became slower when the aggregate length was increased. RBC aggregations with fixed and random lengths and angles resulted in a decorrelation rate that approaches the decorrelation pattern from point scatterers. Results suggests that the presence of aggregates of RBCs will probably not affect the measurements of transverse blood flow using a decorrelation-based method and an IVUS array catheter. |
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Authors:
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F A Lupotti; E I Céspedes; A F van der Steen |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Ultrasound in medicine & biology Volume: 27 ISSN: 0301-5629 ISO Abbreviation: Ultrasound Med Biol Publication Date: 2001 Mar |
Date Detail:
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Created Date: 2001-05-22 Completed Date: 2001-08-09 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0410553 Medline TA: Ultrasound Med Biol Country: England |
Other Details:
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Languages: eng Pagination: 409-17 Citation Subset: IM |
Affiliation:
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Experimental Echocardiography, Thoraxcentre, Erasmus University Rotterdam, Rotterdam, The Netherlands. lupotti@tch.fgg.eur.nl |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Blood Flow Velocity* Catheterization Computer Simulation Erythrocyte Aggregation* Humans Ultrasonography, Interventional* / instrumentation |
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