Document Detail

Declawing of neonatal rabbits destined for use in animal biosafety level 4 containment studies.
MedLine Citation:
PMID:  11178319     Owner:  NLM     Status:  MEDLINE    
To protect personnel and protective outerwear from damage by scratching, rabbits to be housed in an Animal Biosafety Level 4 (ABSL4) facility are declawed routinely. The objective of the study presented here was to establish a procedure for declawing all four feet of neonatal rabbits in preparation for use in ABSL4 studies. Combining procedures conducted in private veterinary practice to remove dewclaws of canine pups with those used to declaw cats, we declawed rabbit kits at 3 to 8 days of age. Declawing neonates was believed to be advantageous because they are non-ambulatory, have soft, cartilaginous digits, and do not have extensive hair growth. These features resulted in decreased surgical preparation and surgery time, minimal bleeding, and minimal aftercare. The optimal age for declawing a litter was 6 or 7 days. Declawing of neonatal rabbits is relatively simple and efficient to perform and offers advantages over declawing of older animals. By using the method described, rabbits can be introduced into ABSL4 facilities by 12 weeks of age with confidence that nail regrowth will not occur.
K A Perdue; R E Shaw; R G Mage
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Contemporary topics in laboratory animal science / American Association for Laboratory Animal Science     Volume:  39     ISSN:  1060-0558     ISO Abbreviation:  Contemp Top Lab Anim Sci     Publication Date:  2000 May 
Date Detail:
Created Date:  2001-02-22     Completed Date:  2001-05-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9204153     Medline TA:  Contemp Top Lab Anim Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  13-8     Citation Subset:  IM    
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
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MeSH Terms
Animals, Laboratory*
Animals, Newborn
Containment of Biohazards / methods*,  veterinary
Hoof and Claw*
Laboratory Personnel*
Occupational Diseases* / prevention & control*
Occupational Health
Protective Clothing
Wounds and Injuries / prevention & control*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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