Document Detail

Decision-making: stenting in acute myocardial infarction.
MedLine Citation:
PMID:  20462337     Owner:  NLM     Status:  MEDLINE    
Percutaneous coronary intervention (PCI) plays a pivotal role in the management of patients with acute myocardial infarction (AMI). Rapid revascularization of the patient with evolving AMI results in reduced rates of mortality, reinfarction and greater myocardial salvage with smaller infarct size. Since the performance of the first balloon angioplasty in 1977, remarkable advances have improved the safety and efficacy of PCI. Advances in stent technology and adjunct pharmacology have improved the outcomes for patients with AMI undergoing primary PCI. Drug-eluting stents result in a significant reduction in the clinical and angiographic rates of restenosis. Early concerns of stent thrombosis in the AMI setting have been allayed by recent results from numerous randomized clinical trials and observational studies. Reduced ischemic and hemorrhagic complications from new antithrombin and antiplatelet agents have further reduced mortality and improved event-free survival after primary PCI.
Somjot S Brar; Gregg W Stone
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Future cardiology     Volume:  6     ISSN:  1744-8298     ISO Abbreviation:  Future Cardiol     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-13     Completed Date:  2010-08-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101239345     Medline TA:  Future Cardiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  301-14     Citation Subset:  IM    
Regional Cardiac Catheterization Laboratory, 4867 Sunset Blvd, 3rd Floor, Room 3755, Kaiser Permanente Medical Center, Los Angeles, CA 90027, USA.
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MeSH Terms
Angioplasty, Transluminal, Percutaneous Coronary
Anticoagulants / therapeutic use
Clinical Trials as Topic
Decision Making
Drug Therapy, Combination
Medication Adherence
Myocardial Infarction / therapy*
Platelet Aggregation Inhibitors / therapeutic use
Risk Factors
Venous Thrombosis / prevention & control
Reg. No./Substance:
0/Anticoagulants; 0/Platelet Aggregation Inhibitors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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