Document Detail


Decidual stromal cells as regulators of T-cell access to the maternal-fetal interface.
MedLine Citation:
PMID:  22935072     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A recent study in the journal Science offers insights into the mechanism behind feto-maternal tolerance, as evidenced by changes in the immuno-logical environment of the uterus and decidua. They also provide a rich area of research for the understanding of the regulation of the immune system in other complicated medical conditions, including cancer and pregnancies affected by infection or autoimmunity.
Authors:
Michelle Silasi; Gil Mor
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2012-08-31
Journal Detail:
Title:  American journal of reproductive immunology (New York, N.Y. : 1989)     Volume:  68     ISSN:  1600-0897     ISO Abbreviation:  Am. J. Reprod. Immunol.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-09-12     Completed Date:  2013-02-05     Revised Date:  2013-10-17    
Medline Journal Info:
Nlm Unique ID:  8912860     Medline TA:  Am J Reprod Immunol     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  279-81     Citation Subset:  IM    
Copyright Information:
© 2012 John Wiley & Sons A/S.
Affiliation:
Reproductive Immunology Unit, Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Cell Communication
Cell Movement / drug effects
Cellular Microenvironment
Chemokine CXCL10 / metabolism
Chemokine CXCL9 / metabolism
Female
Humans
Immune Tolerance
Immunomodulation
Maternal-Fetal Exchange / immunology*
Phenanthridines / immunology*
Pregnancy
Stromal Cells / immunology*
T-Lymphocytes / immunology*
Th1-Th2 Balance
Grant Support
ID/Acronym/Agency:
3N01 HD23342/HD/NICHD NIH HHS; P01 HD054713/HD/NICHD NIH HHS; P01HD054713/HD/NICHD NIH HHS
Chemical
Reg. No./Substance:
0/Chemokine CXCL10; 0/Chemokine CXCL9; 0/Phenanthridines; 123048-04-4/decidium
Comments/Corrections

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