Document Detail

Deceleration vs. acceleration: a haemodynamic parameter in the assessment of vascular reactivity. A preliminary study.
MedLine Citation:
PMID:  7735648     Owner:  NLM     Status:  MEDLINE    
The parameter deceleration vs. acceleration (dc/ac) as derived from the instantaneous peak velocity is obtained by dividing the descending and ascending slopes of plotted velocity curves. Blood velocities were recorded with a specially designed continuous-wave ultrasonic Doppler unit which provides: the instantaneous peak velocity, the instantaneous mean velocity, the acceleration, and an indication of volume flow. A physical meaning to the dc/ac parameter is given through an analysis, based on an electrical model, of a small portion of an artery. This gives a simple relationship which only takes account of the assumed vascular resistances. Measurements were performed in 67 male subjects; 39 were normotensive control subjects and 28 had established moderate hypertension. In both groups there was an increase of dc/ac in passing from the supine to the erect position, the increase being more accentuated by hypertension. The variation of dc/ac with age was significantly different in both groups. The results suggest that this parameter is a sensitive indicator of variations in vascular reactivity and as an indicator of structural changes in the arterial wall.
A Sainz; J Cabau; V C Roberts
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Medical engineering & physics     Volume:  17     ISSN:  1350-4533     ISO Abbreviation:  Med Eng Phys     Publication Date:  1995 Mar 
Date Detail:
Created Date:  1995-06-07     Completed Date:  1995-06-07     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9422753     Medline TA:  Med Eng Phys     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  91-5     Citation Subset:  IM    
Department of Basic Medical Sciences, Universitat de LLeida, Spain.
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MeSH Terms
Biomedical Engineering
Biophysical Phenomena
Blood Flow Velocity / physiology
Hemodynamics / physiology*
Laser-Doppler Flowmetry
Middle Aged
Models, Cardiovascular
Radial Artery / physiology,  ultrasonography
Vascular Resistance / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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